Publi #1 - Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease

Using microfluidics to reconstruct a Huntington’s disease corticostriatal network, Virlogeux et al. identify recurrent pre- and postsynaptic alterations leading to global circuit dysfunctions and hypersynchrony. They further demonstrate that the genetic status of the presynaptic compartment determines integrity of the network.
source: https://www.lemonde.fr/sciences/visuel/2018/01/25/la-maladie-de-huntington-mise-en-microtubes_5246760_1650684.html
Published on November 29, 2018