LPNC Seminar : Leila Reddy - CerCo, Toulouse

on the October 23, 2018

1pm - BSHM A6
leila_reddy



 
Seminar of Leila Reddy - CerCo, Toulouse
Object representations and the influence of learning : insights from single neurons and fMRI patterns
Abstract : Learning associations between co-occurring events enables us to extract structure from our environment. However, the neuronal processes underlying the formation of new associations in the human brain are not yet well understood. Human participants, implanted with depth electrodes, learned arbitrary associations between images presented in an ordered, predictable sequence. During learning we recorded from medial temporal lobe (MTL) neurons and found that single MTL neurons showed asymmetric shifts in activity and started firing earlier in the sequence in anticipation of their preferred stimulus. We also investigated the phase of underlying oscillations at which these cells fired during learning. To investigate the consequences of longer-term associative learning, we performed an fMRI study, in which subjects learned arbitrary new associations between pairs of unrelated objects over 15 days. We found that as a result of this long-term learning, multi-voxel representations of associated objects in the ventral visual pathway, but not the MTL, became more similar to each other. These results demonstrate flexible representations in the MTL that could support rapid learning, while longer-term learning could be reflected in the activity of visual regions.

 

 

Published on October 9, 2018

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Université Grenoble-Alpes 
Laboratoire de Psychologie et Neurocognition
Bâtiment Sciences de l'Homme et Mathématiques
Salle BSHM A6
1251 Avenue Centrale
38400 Saint-Martin-d'Hères